Biophysics of knotting.
نویسندگان
چکیده
Knots appear in a wide variety of biophysical systems, ranging from biopolymers, such as DNA and proteins, to macroscopic objects, such as umbilical cords and catheters. Although significant advancements have been made in the mathematical theory of knots and some progress has been made in the statistical mechanics of knots in idealized chains, the mechanisms and dynamics of knotting in biophysical systems remain far from fully understood. We report on recent progress in the biophysics of knotting-the formation, characterization, and dynamics of knots in various biophysical contexts.
منابع مشابه
A comparative study of knotting decorations and knot tools Used in Ghaffarieh and Kabud domes of Maragheh city
Knotting is one of the most regular geometric decorations that spread with the spread of Islam. Among the different Islamic governments, the Ilkhani era is one of the most brilliant periods of prosperity and flourishing of art and architecture with the use of knot-making in Iran. Among the magnificent buildings of this period are Kabud Dome and Ghaffarieh Dome, located in Maragheh city, the ext...
متن کاملCharacteristic length of random knotting for cylindrical self-avoiding polygons
We discuss the probability of random knotting for a model of self-avoiding polygons whose segments are given by cylinders of unit length with radius r. We show numerically that the characteristic length of random knotting is roughly approximated by an exponential function of the chain thickness r. keyword characteristic length, random knotting, self-avoiding polygons, knot invariants,knots PACS...
متن کاملKnot localization in proteins.
The backbones of proteins form linear chains. In the case of some proteins, these chains can be characterized as forming linear open knots. The knot type of the full chain reveals only limited information about the entanglement of the chain since, for example, subchains of an unknotted protein can form knots and subchains of a knotted protein can form different types of knots than the entire pr...
متن کاملKnotting and Linking in Macromolecules
In the 1980’s, knotting in DNA became a fundamental research dimension in the study of the mechanisms by which enzymes act on it. Later, the first compelling identification of knotting in proteins, in 2000, launched the study of knotting in protein structures and linear macromolecules more generally following on theoretical efforts of the 1960’s. While the linking occurring in structures such a...
متن کاملProteins analysed as virtual knots
Long, flexible physical filaments are naturally tangled and knotted, from macroscopic string down to long-chain molecules. The existence of knotting in a filament naturally affects its configuration and properties, and may be very stable or disappear rapidly under manipulation and interaction. Knotting has been previously identified in protein backbone chains, for which these mechanical constra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annual review of biophysics
دوره 39 شماره
صفحات -
تاریخ انتشار 2010